Concentration-dependent inhibitory effect of Baicalin on the plasma protein binding and metabolism of chlorzoxazone, a CYP2E1 probe substrate, in rats in vitro and in vivo. [electronic resource]
Producer: 20130820Description: e53038 p. digitalISSN:- 1932-6203
- Animals
- Area Under Curve
- Chlorzoxazone -- pharmacology
- Cross-Over Studies
- Cytochrome P-450 CYP2E1 -- metabolism
- Dose-Response Relationship, Drug
- Enzyme Inhibitors -- pharmacology
- Female
- Flavonoids -- pharmacology
- Microsomes, Liver -- metabolism
- Plant Extracts -- pharmacology
- Protein Binding
- Random Allocation
- Rats
- Rats, Sprague-Dawley
- Time Factors
- Treatment Outcome
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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