Vorinostat eliminates multicellular resistance of mesothelioma 3D spheroids via restoration of Noxa expression. [electronic resource]
Producer: 20130627Description: e52753 p. digitalISSN:- 1932-6203
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins -- metabolism
- Bcl-2-Like Protein 11
- Boronic Acids -- pharmacology
- Bortezomib
- Cell Line, Tumor
- Cisplatin -- pharmacology
- Drug Resistance, Neoplasm
- Drug Synergism
- Gene Expression -- drug effects
- Gene Expression Regulation, Neoplastic
- Glutamates -- pharmacology
- Guanine -- analogs & derivatives
- Humans
- Hydroxamic Acids -- pharmacology
- Membrane Proteins -- metabolism
- Mesothelioma
- Myeloid Cell Leukemia Sequence 1 Protein
- Pemetrexed
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- Pyrazines -- pharmacology
- Spheroids, Cellular -- drug effects
- Up-Regulation
- Vorinostat
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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