Sourcing the affinity of flavonoids for the glycogen phosphorylase inhibitor site via crystallography, kinetics and QM/MM-PBSA binding studies: comparison of chrysin and flavopiridol. [electronic resource]
Producer: 20141006Description: 14-27 p. digitalISSN:- 1873-6351
- Adenosine Monophosphate -- metabolism
- Animals
- Binding Sites
- Binding, Competitive
- Chromones -- chemistry
- Crystallography, X-Ray
- Enzyme Inhibitors -- chemistry
- Flavones
- Flavonoids -- chemistry
- Glycogen Phosphorylase -- antagonists & inhibitors
- Kinetics
- Models, Molecular
- Molecular Docking Simulation -- methods
- Piperidines -- chemistry
- Protein Conformation
- Rabbits
- Structure-Activity Relationship
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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