Full-length Plasmodium falciparum circumsporozoite protein administered with long-chain poly(I·C) or the Toll-like receptor 4 agonist glucopyranosyl lipid adjuvant-stable emulsion elicits potent antibody and CD4+ T cell immunity and protection in mice. [electronic resource]
Producer: 20130418Description: 789-800 p. digitalISSN:- 1098-5522
- Animals
- Antibodies, Protozoan -- immunology
- CD4-Positive T-Lymphocytes -- immunology
- Dose-Response Relationship, Immunologic
- Emulsions
- Escherichia coli -- genetics
- Gene Expression Regulation
- Lipids -- chemistry
- Malaria -- prevention & control
- Malaria Vaccines -- immunology
- Mice
- Organisms, Genetically Modified
- Pichia -- genetics
- Plasmodium berghei -- genetics
- Plasmodium falciparum -- immunology
- Protozoan Proteins -- genetics
- Time Factors
- Toll-Like Receptor 4 -- agonists
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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