Epidithiodiketopiperazine as a pharmacophore for protein lysine methyltransferase G9a inhibitors: reducing cytotoxicity by structural simplification. [electronic resource]
Producer: 20130625Description: 733-6 p. digitalISSN:- 1464-3405
- Cell Survival -- drug effects
- Chaetomium -- chemistry
- Diketopiperazines -- chemical synthesis
- Enzyme Inhibitors -- chemical synthesis
- HL-60 Cells
- Histone-Lysine N-Methyltransferase -- antagonists & inhibitors
- Humans
- Molecular Structure
- Piperazines -- chemical synthesis
- Structure-Activity Relationship
- Thioredoxin-Disulfide Reductase -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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