γ-H2AX+CD8+ T lymphocytes cannot respond to IFN-α, IL-2 or IL-6 in chronic hepatitis C virus infection. [electronic resource]
Producer: 20140211Description: 868-74 p. digitalISSN:- 1600-0641
- Adult
- Biopsy
- CD8-Positive T-Lymphocytes -- drug effects
- Case-Control Studies
- Cells, Cultured
- DNA
- DNA Damage
- Female
- Hepacivirus -- isolation & purification
- Hepatitis C, Chronic -- metabolism
- Histones -- metabolism
- Humans
- In Vitro Techniques
- Interferon-alpha -- pharmacology
- Interleukin-2 -- pharmacology
- Interleukin-6 -- pharmacology
- Liver -- metabolism
- Male
- Middle Aged
- STAT1 Transcription Factor -- metabolism
- STAT5 Transcription Factor -- metabolism
- Telomere Shortening
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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