Controlled release of simvastatin from in situ forming hydrogel triggers bone formation in MC3T3-E1 cells. [electronic resource]
Producer: 20131022Description: 367-76 p. digitalISSN:- 1550-7416
- Animals
- Biomarkers -- metabolism
- Blotting, Western
- Bone Density Conservation Agents -- chemistry
- Buffers
- Cell Differentiation -- drug effects
- Cell Line
- Cell Proliferation -- drug effects
- Chemistry, Pharmaceutical
- Cross-Linking Reagents -- chemistry
- Delayed-Action Preparations
- Dose-Response Relationship, Drug
- Drug Compounding
- Gelatin -- chemistry
- Horseradish Peroxidase -- chemistry
- Hydrogels
- Hydrogen Peroxide -- chemistry
- Hydrogen-Ion Concentration
- Kinetics
- Matrix Metalloproteinase 13 -- genetics
- Mice
- Osteoblasts -- drug effects
- Osteocalcin -- genetics
- Osteogenesis -- drug effects
- Polyethylene Glycols -- chemistry
- Polymerase Chain Reaction
- Simvastatin -- chemistry
- Solubility
- Technology, Pharmaceutical -- methods
- Tyramine -- analogs & derivatives
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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