The influence of sex, ethnicity, and CYP2B6 genotype on bupropion metabolism as an index of hepatic CYP2B6 activity in humans. [electronic resource]
Producer: 20130712Description: 575-81 p. digitalISSN:- 1521-009X
- Administration, Oral
- Adolescent
- Adult
- Black or African American -- genetics
- Antidepressive Agents -- administration & dosage
- Aryl Hydrocarbon Hydroxylases -- genetics
- Biotransformation
- Bupropion -- administration & dosage
- Cytochrome P-450 CYP2B6
- Delayed-Action Preparations
- Ethnicity -- genetics
- Female
- Genotype
- Hispanic or Latino -- genetics
- Humans
- Linear Models
- Liver -- enzymology
- Male
- Middle Aged
- Oxidoreductases, N-Demethylating -- genetics
- Pharmacogenetics
- Phenotype
- Polymorphism, Genetic
- Sex Factors
- Substrate Specificity
- White People -- genetics
- Young Adult
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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