Hepatitis C virus mediated changes in miRNA-449a modulates inflammatory biomarker YKL40 through components of the NOTCH signaling pathway. [electronic resource]
Producer: 20130528Description: e50826 p. digitalISSN:- 1932-6203
- Adipokines -- genetics
- Adult
- Base Sequence
- Biomarkers -- metabolism
- CCAAT-Enhancer-Binding Proteins -- metabolism
- Chitinase-3-Like Protein 1
- Down-Regulation -- drug effects
- Female
- Hepacivirus -- physiology
- Hepatitis C -- complications
- Hepatocytes -- drug effects
- Humans
- Inflammation -- complications
- Lectins -- genetics
- Liver Cirrhosis -- complications
- Male
- MicroRNAs -- genetics
- Middle Aged
- Models, Biological
- Molecular Sequence Data
- Mutation -- genetics
- NF-kappa B -- metabolism
- Promoter Regions, Genetic -- genetics
- Receptor, Notch1 -- metabolism
- Signal Transduction -- drug effects
- Transcription, Genetic -- drug effects
- Tumor Necrosis Factor-alpha -- metabolism
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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