A novel Rac1 GAP splice variant relays poly-Ub accumulation signals to mediate Rac1 inactivation. [electronic resource]
Producer: 20130723Description: 194-209 p. digitalISSN:- 1939-4586
- Alzheimer Disease -- metabolism
- Amino Acid Sequence
- Amyloid beta-Protein Precursor -- metabolism
- Brain -- metabolism
- Cell Membrane -- enzymology
- GTPase-Activating Proteins -- chemistry
- Gene Knockdown Techniques
- HEK293 Cells
- HeLa Cells
- Humans
- Leupeptins -- pharmacology
- Molecular Sequence Data
- NADPH Oxidase 1
- NADPH Oxidases -- metabolism
- Phosphoric Monoester Hydrolases -- chemistry
- Polyubiquitin -- metabolism
- Proteasome Inhibitors -- pharmacology
- Protein Isoforms -- chemistry
- Protein Structure, Tertiary
- Protein Transport
- RNA, Small Interfering -- genetics
- Reactive Oxygen Species -- metabolism
- Signal Transduction
- cdc42 GTP-Binding Protein -- metabolism
- rac1 GTP-Binding Protein -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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