Progesterone acts via the nuclear glucocorticoid receptor to suppress IL-1β-induced COX-2 expression in human term myometrial cells. [electronic resource]
Producer: 20130624Description: e50167 p. digitalISSN:- 1932-6203
- Cell Nucleus -- metabolism
- Cells, Cultured
- Cyclooxygenase 2 -- metabolism
- Estrenes -- pharmacology
- Female
- Furans -- pharmacology
- Gene Expression Regulation
- Gene Expression Regulation, Enzymologic
- Gene Silencing
- Genes, Reporter
- Humans
- Interleukin-1beta -- metabolism
- Mifepristone -- pharmacology
- Myometrium -- metabolism
- NF-kappa B -- metabolism
- Progesterone -- metabolism
- RNA, Small Interfering -- metabolism
- Receptors, Glucocorticoid -- metabolism
- Receptors, Progesterone -- metabolism
- Transcription Factor RelA -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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