15-Deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2) protects neurons from oxidative death via an Nrf2 astrocyte-specific mechanism independent of PPARγ. [electronic resource]
Producer: 20130318Description: 536-47 p. digitalISSN:- 1471-4159
- Animals
- Astrocytes -- metabolism
- Cell Count
- Cells, Cultured
- Dose-Response Relationship, Drug
- Drug Interactions
- Glutathione -- metabolism
- Homocysteine -- analogs & derivatives
- Hypoglycemic Agents -- pharmacology
- Microtubule-Associated Proteins -- metabolism
- NF-E2-Related Factor 2 -- metabolism
- Neurons -- drug effects
- Neuroprotective Agents -- pharmacology
- Oxidative Stress -- drug effects
- PPAR gamma -- pharmacology
- Prostaglandin D2 -- analogs & derivatives
- RNA, Small Interfering -- pharmacology
- Rats
- Thiazolidinediones -- pharmacology
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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