Platelet-rich plasma greatly potentiates insulin-induced adipogenic differentiation of human adipose-derived stem cells through a serine/threonine kinase Akt-dependent mechanism and promotes clinical fat graft maintenance. [electronic resource]
Producer: 20130110Description: 206-20 p. digitalISSN:- 2157-6564
- Adipogenesis -- drug effects
- Adipose Tissue -- cytology
- Adolescent
- Adult
- Aged
- Apoptosis
- Blotting, Western
- Cell Differentiation -- drug effects
- Cell Proliferation
- Female
- Fibroblast Growth Factor 2 -- pharmacology
- Flow Cytometry
- Graft Survival -- physiology
- Humans
- Hypoglycemic Agents -- pharmacology
- Immunoenzyme Techniques
- Insulin -- pharmacology
- Male
- Middle Aged
- Phosphorylation -- drug effects
- Platelet-Rich Plasma -- metabolism
- Proto-Oncogene Proteins c-akt -- genetics
- RNA, Messenger -- genetics
- Real-Time Polymerase Chain Reaction
- Receptor, ErbB-2 -- genetics
- Receptor, Fibroblast Growth Factor, Type 1 -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction -- drug effects
- Stem Cells -- cytology
- Young Adult
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Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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