Wnt signaling orchestration with a small molecule DYRK inhibitor provides long-term xeno-free human pluripotent cell expansion. [electronic resource]
Producer: 20130103Description: 18-28 p. digitalISSN:- 2157-6564
- Animals
- Cell Culture Techniques
- Cell Differentiation -- drug effects
- Cell Line
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- Embryonic Stem Cells -- drug effects
- Gene Knockdown Techniques
- Humans
- Induced Pluripotent Stem Cells -- drug effects
- Karyotyping
- Mice
- Mice, SCID
- Protein Kinase Inhibitors -- pharmacology
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- RNA Interference
- Time Factors
- Wnt Signaling Pathway -- drug effects
- Wnt3A Protein -- metabolism
- Dyrk Kinases
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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