Human paraoxonase double mutants hydrolyze V and G class organophosphorus nerve agents. [electronic resource]
Producer: 20130528Description: 181-5 p. digitalISSN:- 1872-7786
- Amino Acid Substitution
- Antidotes -- metabolism
- Aryldialkylphosphatase -- chemistry
- Catalytic Domain -- genetics
- Chemical Warfare Agents -- classification
- Humans
- Hydrolysis
- Kinetics
- Models, Molecular
- Mutagenesis, Site-Directed
- Mutant Proteins -- chemistry
- Organophosphates -- metabolism
- Organophosphorus Compounds -- classification
- Organothiophosphorus Compounds -- metabolism
- Paraoxon -- classification
- Protein Engineering
- Recombinant Proteins -- chemistry
- Sarin -- metabolism
- Soman -- metabolism
- Substrate Specificity
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
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