Synthesis and biological evaluation of novel antifolate analogs as potential anticancer treatment. [electronic resource]
Producer: 20130805Description: 364-72 p. digitalISSN:- 1875-5992
- Animals
- Antineoplastic Agents -- chemical synthesis
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- Female
- Folic Acid Antagonists -- chemical synthesis
- Humans
- Mice
- Mice, Inbred DBA
- Molecular Structure
- Neoplasms -- drug therapy
- Structure-Activity Relationship
- Tetrahydrofolate Dehydrogenase -- metabolism
- Thymidylate Synthase -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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