Suppression of HIV-1 infection by APOBEC3 proteins in primary human CD4(+) T cells is associated with inhibition of processive reverse transcription as well as excessive cytidine deamination. [electronic resource]
Producer: 20130305Description: 1508-17 p. digitalISSN:- 1098-5514
- APOBEC-3G Deaminase
- CD4-Positive T-Lymphocytes -- enzymology
- Cells, Cultured
- Cytidine -- metabolism
- Cytidine Deaminase -- metabolism
- Cytosine Deaminase -- metabolism
- Deamination
- Gene Deletion
- HIV-1 -- genetics
- Humans
- Reverse Transcription
- Virulence Factors -- genetics
- vif Gene Products, Human Immunodeficiency Virus -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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