Inactivation of tankyrases reduces experimental fibrosis by inhibiting canonical Wnt signalling. [electronic resource]
Producer: 20131017Description: 1575-80 p. digitalISSN:- 1468-2060
- Animals
- Cell Differentiation -- drug effects
- Collagen -- metabolism
- Disease Models, Animal
- Fibroblasts -- drug effects
- Fibrosis -- drug therapy
- Gene Expression Regulation, Enzymologic -- drug effects
- Gene Knockdown Techniques
- Gene Silencing
- Genes, myc -- drug effects
- Heterocyclic Compounds, 3-Ring -- pharmacology
- Mice
- Molecular Targeted Therapy
- Myofibroblasts -- drug effects
- RNA, Small Interfering -- pharmacology
- Scleroderma, Systemic -- drug therapy
- Skin Diseases -- drug therapy
- Tankyrases -- antagonists & inhibitors
- Wnt Signaling Pathway -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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