Effect of CYP3A5, CYP3A4, and ABCB1 genotypes as determinants of tacrolimus dose and clinical outcomes after heart transplantation. [electronic resource]
Producer: 20130613Description: 2635-8 p. digitalISSN:- 1873-2623
- ATP Binding Cassette Transporter, Subfamily B
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- genetics
- Adult
- Analysis of Variance
- Cytochrome P-450 CYP3A -- genetics
- Diabetes Mellitus -- chemically induced
- Female
- Genetic Predisposition to Disease
- Graft Rejection -- genetics
- Graft Survival -- drug effects
- Heart Transplantation -- adverse effects
- Homozygote
- Humans
- Immunosuppressive Agents -- administration & dosage
- Linear Models
- Logistic Models
- Male
- Middle Aged
- Phenotype
- Polymorphism, Single Nucleotide
- Risk Assessment
- Risk Factors
- Tacrolimus -- administration & dosage
- Treatment Outcome
- Young Adult
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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