Cohesion fatigue explains why pharmacological inhibition of the APC/C induces a spindle checkpoint-dependent mitotic arrest. [electronic resource]
Producer: 20130724Description: e49041 p. digitalISSN:- 1932-6203
- Anaphase-Promoting Complex-Cyclosome
- Cell Cycle Proteins -- genetics
- Cell Line, Tumor
- Chromosome Segregation -- genetics
- Chromosomes -- genetics
- HeLa Cells
- Humans
- Kinetochores -- metabolism
- Metaphase -- genetics
- Mitosis -- drug effects
- Proteasome Endopeptidase Complex -- genetics
- Spindle Apparatus -- drug effects
- Tosylarginine Methyl Ester -- pharmacology
- Ubiquitin-Protein Ligase Complexes -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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