Trans-chromosomic mice containing a human CYP3A cluster for prediction of xenobiotic metabolism in humans. [electronic resource]
Producer: 20130701Description: 578-92 p. digitalISSN:- 1460-2083
- Animals
- Aryl Hydrocarbon Hydroxylases -- genetics
- Blotting, Southern
- CHO Cells
- Cell Line
- Chromosomes, Artificial, Human
- Chromosomes, Human, Pair 7
- Cloning, Molecular
- Cricetinae
- Cytochrome P-450 CYP3A -- genetics
- Dehydroepiandrosterone -- metabolism
- Female
- Gene Expression Regulation, Enzymologic
- Genetic Loci
- Humans
- Inactivation, Metabolic
- Intestines -- enzymology
- Liver -- enzymology
- Mice
- Mice, Inbred ICR
- Mice, Transgenic
- Microsomes -- metabolism
- Multigene Family
- Triazolam -- pharmacokinetics
- Xenobiotics -- metabolism
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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