Loss of the oxidative stress sensor NPGPx compromises GRP78 chaperone activity and induces systemic disease. [electronic resource]
Producer: 20130219Description: 747-59 p. digitalISSN:- 1097-4164
- Animals
- Carrier Proteins -- genetics
- Cell Line, Tumor
- Cell Proliferation
- Cell Survival
- Cell Transformation, Neoplastic -- genetics
- Cysteine
- DNA Damage
- Disulfides -- metabolism
- Dose-Response Relationship, Drug
- Endoplasmic Reticulum Chaperone BiP
- Endoplasmic Reticulum Stress -- drug effects
- Fibroblasts -- enzymology
- Glutathione Peroxidase
- Heat-Shock Proteins -- genetics
- Homeostasis
- Humans
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Mutagenesis, Site-Directed
- Mutation
- Oxidants -- pharmacology
- Oxidation-Reduction
- Oxidative Stress -- drug effects
- Peroxidases -- genetics
- Protein Binding
- Protein Folding
- Proteostasis Deficiencies -- enzymology
- Reactive Oxygen Species -- metabolism
- Signal Transduction -- drug effects
- Time Factors
- Transfection
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.