Metalloproteinases and their associated genes contribute to the functional integrity and noise-induced damage in the cochlear sensory epithelium. [electronic resource]
Producer: 20130107Description: 14927-41 p. digitalISSN:- 1529-2401
- Acoustic Stimulation
- Analysis of Variance
- Animals
- Cochlea -- pathology
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Doxycycline -- toxicity
- Enzyme Inhibitors -- pharmacology
- Epithelium -- metabolism
- Evoked Potentials, Auditory, Brain Stem -- genetics
- Female
- Fluorescence Resonance Energy Transfer
- Gene Expression Regulation -- drug effects
- Hearing Loss, Noise-Induced -- chemically induced
- Male
- Matrix Metalloproteinase 7 -- deficiency
- Matrix Metalloproteinases -- metabolism
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- RNA, Messenger -- metabolism
- Rats
- Rats, Sprague-Dawley
- Tissue Inhibitor of Metalloproteinase-1 -- metabolism
- Tissue Inhibitor of Metalloproteinase-2 -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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