PPARα agonist Wy14643 suppresses cathepsin B in human endothelial cells via transcriptional, post-transcriptional and post-translational mechanisms. [electronic resource]
Producer: 20130530Description: 223-33 p. digitalISSN:- 1573-7209
- Alternative Splicing -- drug effects
- Base Pairing -- genetics
- Blotting, Western
- Cathepsin B -- genetics
- Down-Regulation -- drug effects
- E-Box Elements -- genetics
- Exons -- genetics
- Half-Life
- Human Umbilical Vein Endothelial Cells -- drug effects
- Humans
- PPAR alpha -- agonists
- Promoter Regions, Genetic -- genetics
- Protein Binding -- drug effects
- Protein Processing, Post-Translational -- drug effects
- Pyrimidines -- pharmacology
- RNA, Messenger -- genetics
- Subcellular Fractions -- drug effects
- Transcription, Genetic -- drug effects
- Upstream Stimulatory Factors -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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