Small-animal SPECT/CT of HER2 and HER3 expression in tumor xenografts in athymic mice using trastuzumab Fab-heregulin bispecific radioimmunoconjugates. [electronic resource]
Producer: 20130205Description: 1943-50 p. digitalISSN:- 1535-5667
- Animals
- Antibodies, Bispecific -- immunology
- Antibodies, Monoclonal, Humanized -- immunology
- Biological Transport
- Cell Line, Tumor
- Cell Transformation, Neoplastic
- Gene Expression Regulation, Neoplastic
- Humans
- Immunoconjugates -- immunology
- Immunoglobulin Fab Fragments -- immunology
- Indium Radioisotopes
- Mice
- Mice, Nude
- Multimodal Imaging -- methods
- Neuregulin-1 -- metabolism
- Positron-Emission Tomography
- Protein Multimerization
- Receptor, ErbB-2 -- chemistry
- Receptor, ErbB-3 -- chemistry
- Tomography, X-Ray Computed
- Trastuzumab
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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