Cytotoxicity and cell death mechanisms induced by a novel bisnaphthalimidopropyl derivative against the NCI-H460 non-small lung cancer cell line. [electronic resource]
Producer: 20130805Description: 414-21 p. digitalISSN:- 1875-5992
- Acetylation
- Antineoplastic Agents -- chemical synthesis
- Apoptosis -- drug effects
- Biogenic Polyamines -- chemical synthesis
- Caspase 3 -- genetics
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Cyclohexylamines -- chemical synthesis
- Dose-Response Relationship, Drug
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Molecular Docking Simulation
- Naphthalimides -- chemical synthesis
- Poly(ADP-ribose) Polymerase Inhibitors
- Poly(ADP-ribose) Polymerases -- genetics
- Quinolones -- chemical synthesis
- Signal Transduction -- drug effects
- Sirtuin 1 -- antagonists & inhibitors
- Sirtuin 2 -- antagonists & inhibitors
- Structure-Activity Relationship
- Tubulin -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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