Chloroquine or chloroquine-PI3K/Akt pathway inhibitor combinations strongly promote γ-irradiation-induced cell death in primary stem-like glioma cells. [electronic resource]
Producer: 20130328Description: e47357 p. digitalISSN:- 1932-6203
- Apoptosis -- drug effects
- Autophagy -- drug effects
- Cell Line, Tumor
- Chloroquine -- pharmacology
- Drug Synergism
- Enzyme Inhibitors -- pharmacology
- Gamma Rays -- adverse effects
- Glioma -- metabolism
- Humans
- Neoplastic Stem Cells -- drug effects
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphoinositide-3 Kinase Inhibitors
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Signal Transduction -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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