Transduction of human CD34+ repopulating cells with a self-inactivating lentiviral vector for SCID-X1 produced at clinical scale by a stable cell line. [electronic resource]
Producer: 20130718Description: 297-308 p. digitalISSN:- 1946-6544
- Animals
- Antigens, CD34
- Bioreactors
- Cell Line
- Disease Models, Animal
- Female
- Genetic Therapy
- Genetic Vectors -- genetics
- Hematopoietic Stem Cell Transplantation
- Hematopoietic Stem Cells -- metabolism
- Humans
- Lentivirus -- genetics
- Lymphocytes -- cytology
- Mice
- Myeloid Cells -- cytology
- Transduction, Genetic
- Transplantation, Heterologous
- X-Linked Combined Immunodeficiency Diseases -- therapy
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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