Molecular dynamics and tubulin polymerization kinetics study on 1,14-heterofused taxanes: evidence of stabilization of the tubulin head-to-tail dimer-dimer interaction. [electronic resource]
Producer: 20130502Description: 3254-61 p. digitalISSN:- 1742-2051
- Bridged-Ring Compounds -- metabolism
- Cell Line, Tumor
- Computational Biology
- Humans
- Kinetics
- MCF-7 Cells
- Microtubules -- chemistry
- Models, Molecular
- Molecular Dynamics Simulation
- Paclitaxel -- analogs & derivatives
- Protein Binding
- Protein Conformation
- Protein Multimerization
- Taxoids -- metabolism
- Tubulin -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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