TGF-β signaling, activated stromal fibroblasts, and cysteine cathepsins B and L drive the invasive growth of human melanoma cells. [electronic resource]
Producer: 20130501Description: 2202-16 p. digitalISSN:- 1525-2191
- Adult
- Cathepsin B -- antagonists & inhibitors
- Cathepsin L -- antagonists & inhibitors
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Embryo, Mammalian -- pathology
- Fibroblasts -- drug effects
- Fluorescent Dyes -- metabolism
- Gene Expression Profiling
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Matrix Metalloproteinases -- metabolism
- Melanoma -- enzymology
- Neoplasm Invasiveness
- Nevus -- enzymology
- Oligonucleotide Array Sequence Analysis
- Protease Inhibitors -- pharmacology
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Receptor, Transforming Growth Factor-beta Type I
- Receptors, Transforming Growth Factor beta -- antagonists & inhibitors
- Signal Transduction -- drug effects
- Skin -- pathology
- Skin Neoplasms -- enzymology
- Stromal Cells -- drug effects
- Transforming Growth Factor beta -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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