Design, synthesis and biological evaluation of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3β (GSK-3β). [electronic resource]
Producer: 20140826Description: 95-103 p. digitalISSN:- 1768-3254
- Benzazepines -- chemical synthesis
- Binding, Competitive -- drug effects
- Crystallography, X-Ray
- Dose-Response Relationship, Drug
- Drug Design
- Glycogen Synthase Kinase 3 -- antagonists & inhibitors
- Glycogen Synthase Kinase 3 beta
- Humans
- Models, Molecular
- Molecular Structure
- Protein Kinase Inhibitors -- chemical synthesis
- Recombinant Proteins -- metabolism
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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