IL-15 augments TCR-induced CD4+ T cell expansion in vitro by inhibiting the suppressive function of CD25 High CD4+ T cells. [electronic resource]
Producer: 20130228Description: e45299 p. digitalISSN:- 1932-6203
- Animals
- Antigens, CD -- genetics
- CD4-Positive T-Lymphocytes -- cytology
- CD8-Positive T-Lymphocytes -- cytology
- Cell Proliferation -- drug effects
- Cells, Cultured
- Cyclosporine -- pharmacology
- Flow Cytometry
- Forkhead Transcription Factors -- genetics
- Gene Expression Regulation -- drug effects
- Humans
- Immune Tolerance
- Interleukin-15 -- immunology
- Interleukin-15 Receptor alpha Subunit -- genetics
- Interleukin-2 -- biosynthesis
- Interleukin-2 Receptor beta Subunit -- genetics
- Lymphocyte Activation -- drug effects
- Mice
- Receptors, Antigen, T-Cell -- immunology
- Signal Transduction -- drug effects
- T-Lymphocytes, Regulatory -- cytology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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