Doxorubicin induces cytotoxicity through upregulation of pERK-dependent ATF3. [electronic resource]
Producer: 20130226Description: e44990 p. digitalISSN:- 1932-6203
- Activating Transcription Factor 3 -- genetics
- Animals
- Cell Cycle -- drug effects
- Cell Death -- drug effects
- Cell Line
- Cell Proliferation -- drug effects
- Doxorubicin -- toxicity
- Embryo, Mammalian -- cytology
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Fibroblasts -- cytology
- Gene Silencing -- drug effects
- Humans
- Interleukin-6 -- metabolism
- Kidney Tubules, Proximal -- cytology
- Mice
- Mice, Knockout
- Nitric Oxide -- metabolism
- Phosphorylation -- drug effects
- RNA, Messenger -- genetics
- RNA, Small Interfering -- metabolism
- Tumor Necrosis Factor-alpha -- metabolism
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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