H1N1 2009 pandemic influenza virus: resistance of the I223R neuraminidase mutant explained by kinetic and structural analysis. [electronic resource]
Producer: 20130509Description: e1002914 p. digitalISSN:- 1553-7374
- Adamantane -- pharmacology
- Amino Acid Substitution
- Antiviral Agents -- pharmacology
- Binding Sites -- genetics
- Crystallography, X-Ray
- Drug Resistance, Viral -- genetics
- Enzyme Inhibitors -- pharmacology
- Humans
- Hydrophobic and Hydrophilic Interactions
- Influenza A Virus, H1N1 Subtype -- drug effects
- Influenza, Human -- drug therapy
- Mutation
- Neuraminidase -- antagonists & inhibitors
- Oseltamivir -- pharmacology
- Pandemics
- Protein Conformation
- Zanamivir -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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