Small-molecule structure correctors target abnormal protein structure and function: structure corrector rescue of apolipoprotein E4-associated neuropathology. [electronic resource]
Producer: 20130226Description: 8997-9008 p. digitalISSN:- 1520-4804
- Alzheimer Disease -- drug therapy
- Animals
- Apolipoprotein E4 -- chemistry
- Brain Injuries -- metabolism
- Endoplasmic Reticulum -- metabolism
- Golgi Apparatus -- metabolism
- Humans
- Lipid Metabolism
- Models, Molecular
- Molecular Targeted Therapy
- Neurons -- metabolism
- Protein Conformation
- Protein Folding -- drug effects
- Protein Transport
- Proteostasis Deficiencies -- drug therapy
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
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