The ADP receptor P2RY12 regulates osteoclast function and pathologic bone remodeling. [electronic resource]
Producer: 20130201Description: 3579-92 p. digitalISSN:- 1558-8238
- Adenosine Diphosphate -- physiology
- Animals
- Arthritis, Experimental -- complications
- Bone Neoplasms -- complications
- Bone Remodeling -- drug effects
- Bone Resorption -- physiopathology
- Carcinoma -- complications
- Cell Adhesion -- drug effects
- Cells, Cultured -- drug effects
- Clopidogrel
- Enzyme Activation -- drug effects
- Female
- Mammary Neoplasms, Experimental -- pathology
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Osteoclasts -- physiology
- Osteoporosis -- etiology
- Ovariectomy
- Phosphatidylinositol 3-Kinases -- physiology
- Phosphoinositide-3 Kinase Inhibitors
- Platelet Glycoprotein GPIIb-IIIa Complex -- drug effects
- Purinergic P2Y Receptor Antagonists -- pharmacology
- Receptors, Purinergic P2Y12 -- deficiency
- Specific Pathogen-Free Organisms
- Ticlopidine -- analogs & derivatives
- rap1 GTP-Binding Proteins -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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