Phlorofucofuroeckol A suppresses expression of inducible nitric oxide synthase, cyclooxygenase-2, and pro-inflammatory cytokines via inhibition of nuclear factor-κB, c-Jun NH2-terminal kinases, and Akt in microglial cells. [electronic resource]
Producer: 20130823Description: 259-71 p. digitalISSN:- 1573-2576
- Animals
- Benzofurans -- pharmacology
- Cyclooxygenase 2 -- biosynthesis
- Cytokines -- biosynthesis
- Dinoprostone -- biosynthesis
- Dioxins -- pharmacology
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- I-kappa B Proteins -- drug effects
- JNK Mitogen-Activated Protein Kinases -- antagonists & inhibitors
- MAP Kinase Signaling System -- drug effects
- Mice
- Microglia -- drug effects
- NF-KappaB Inhibitor alpha
- NF-kappa B -- antagonists & inhibitors
- Nitric Oxide -- biosynthesis
- Nitric Oxide Synthase Type II -- biosynthesis
- Phaeophyceae
- Plant Extracts -- pharmacology
- Protein Transport -- drug effects
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Reactive Oxygen Species
- Transcription Factor RelA -- drug effects
- p38 Mitogen-Activated Protein Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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