Saucerneol D inhibits eicosanoid generation and degranulation through suppression of Syk kinase in mast cells. [electronic resource]
Producer: 20130408Description: 4382-8 p. digitalISSN:- 1873-6351
- Animals
- Arachidonate 5-Lipoxygenase -- genetics
- Bone Marrow Cells -- cytology
- Cell Degranulation -- drug effects
- Cyclooxygenase 2 -- genetics
- Eicosanoids -- antagonists & inhibitors
- Intracellular Signaling Peptides and Proteins -- genetics
- Leukotriene C4 -- genetics
- Lignans -- pharmacology
- MAP Kinase Signaling System
- Male
- Mast Cells -- drug effects
- Mice
- Mice, Inbred BALB C
- Mitogen-Activated Protein Kinase 3 -- metabolism
- Mitogen-Activated Protein Kinases -- metabolism
- NF-kappa B -- metabolism
- Phospholipase C gamma -- genetics
- Phosphorylation
- Plant Extracts -- pharmacology
- Protein-Tyrosine Kinases -- genetics
- Saururaceae -- chemistry
- Syk Kinase
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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