Suppression of acquired docetaxel resistance in prostate cancer through depletion of notch- and hedgehog-dependent tumor-initiating cells. [electronic resource]
Producer: 20121126Description: 373-88 p. digitalISSN:- 1878-3686
- Animals
- Apoptosis
- Cell Line, Tumor
- Disease Progression
- Docetaxel
- Drug Resistance, Neoplasm
- Hedgehog Proteins -- genetics
- Humans
- Male
- Mice
- Mice, Inbred NOD
- Mice, SCID
- Molecular Sequence Data
- Neoplastic Stem Cells -- metabolism
- Prostatic Neoplasms -- drug therapy
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Proto-Oncogene Proteins c-bcl-2 -- antagonists & inhibitors
- Receptors, Notch -- genetics
- Signal Transduction
- Taxoids -- pharmacology
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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