EGCG inhibits growth of human pancreatic tumors orthotopically implanted in Balb C nude mice through modulation of FKHRL1/FOXO3a and neuropilin. [electronic resource]
Producer: 20130515Description: 83-94 p. digitalISSN:- 1573-4919
- Animals
- Antineoplastic Agents, Phytogenic -- pharmacology
- Apoptosis -- drug effects
- Biomarkers, Tumor -- genetics
- Carcinoma, Pancreatic Ductal -- blood supply
- Catechin -- analogs & derivatives
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Forkhead Box Protein O3
- Forkhead Transcription Factors -- metabolism
- Gene Expression -- drug effects
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- MAP Kinase Signaling System -- drug effects
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Neovascularization, Pathologic -- prevention & control
- Neuropilins -- metabolism
- Pancreas -- pathology
- Pancreatic Neoplasms -- blood supply
- Proliferating Cell Nuclear Antigen -- metabolism
- Tumor Burden -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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