Transgenic inhibition of astroglial NF-κB protects from optic nerve damage and retinal ganglion cell loss in experimental optic neuritis. [electronic resource]
Producer: 20130419Description: 213 p. digitalISSN:- 1742-2094
- Analysis of Variance
- Animals
- Astrocytes -- metabolism
- Cell Count
- Cytokines -- metabolism
- Disease Models, Animal
- Encephalomyelitis, Autoimmune, Experimental -- chemically induced
- Glial Fibrillary Acidic Protein -- genetics
- Membrane Glycoproteins -- metabolism
- Mice
- Mice, Transgenic
- Myelin-Oligodendrocyte Glycoprotein -- toxicity
- NADPH Oxidase 2
- NADPH Oxidases -- metabolism
- NF-kappa B -- genetics
- Neutrophil Infiltration -- drug effects
- Optic Nerve -- metabolism
- Optic Nerve Diseases -- etiology
- Oxidative Stress -- physiology
- Peptide Fragments -- toxicity
- Phenylenediamines -- metabolism
- Phosphopyruvate Hydratase -- metabolism
- Retinal Ganglion Cells -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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