Design, activity, and 2.8 A crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease. [electronic resource]
Producer: 19900912Description: 527-33 p. digitalISSN:- 0036-8075
- Amino Acid Sequence
- Binding Sites
- Drug Design
- Endopeptidases -- metabolism
- Gene Products, pol -- metabolism
- HIV Protease
- HIV-1 -- enzymology
- Kinetics
- Models, Molecular
- Molecular Sequence Data
- Protease Inhibitors -- pharmacology
- Protein Conformation
- Sugar Alcohols -- pharmacology
- Valine -- analogs & derivatives
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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