Autoantibodies specific to a peptide of β2-glycoprotein I cross-react with TLR4, inducing a proinflammatory phenotype in endothelial cells and monocytes. [electronic resource]
Producer: 20130117Description: 3360-70 p. digitalISSN:- 1528-0020
- Adolescent
- Adult
- Aged
- Antiphospholipid Syndrome -- immunology
- Autoantibodies -- blood
- Case-Control Studies
- Chronic Periodontitis -- immunology
- Cross Reactions
- Enzyme-Linked Immunosorbent Assay
- Female
- Human Umbilical Vein Endothelial Cells -- immunology
- Humans
- Inflammation Mediators -- metabolism
- Lupus Erythematosus, Systemic -- immunology
- Male
- Middle Aged
- Monocytes -- immunology
- NF-kappa B -- metabolism
- Peptide Fragments -- immunology
- Protein Transport
- RNA, Small Interfering -- genetics
- Toll-Like Receptor 4 -- antagonists & inhibitors
- Tumor Necrosis Factor-alpha -- metabolism
- Young Adult
- beta 2-Glycoprotein I -- immunology
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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