Hypoxia-inducible factor-1 (HIF-1) but not HIF-2 is essential for hypoxic induction of collagen prolyl 4-hydroxylases in primary newborn mouse epiphyseal growth plate chondrocytes. [electronic resource]
Producer: 20130107Description: 37134-44 p. digitalISSN:- 1083-351X
- Animals
- Animals, Newborn
- Basic Helix-Loop-Helix Transcription Factors -- genetics
- Cell Hypoxia -- genetics
- Cells, Cultured
- Chondrocytes -- enzymology
- Gene Expression Regulation, Enzymologic
- Gene Knockdown Techniques
- Growth Plate -- cytology
- Humans
- Hydroxyproline -- biosynthesis
- Hypoxia-Inducible Factor 1, alpha Subunit -- genetics
- Mice
- Primary Cell Culture
- Procollagen-Proline Dioxygenase -- genetics
- Protein Multimerization
- Transcription, Genetic
- Transcriptional Activation
- Von Hippel-Lindau Tumor Suppressor Protein -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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