The multiobjective based design, synthesis and evaluation of the arylsulfonamide/amide derivatives of aryloxyethyl- and arylthioethyl- piperidines and pyrrolidines as a novel class of potent 5-HT₇ receptor antagonists. [electronic resource]
Producer: 20130509Description: 348-60 p. digitalISSN:- 1768-3254
- Amides -- chemistry
- Cells, Cultured
- Combinatorial Chemistry Techniques
- Dose-Response Relationship, Drug
- Drug Design
- HEK293 Cells
- Humans
- Ligands
- Models, Molecular
- Molecular Structure
- Piperidines -- chemical synthesis
- Pyrrolidines -- chemical synthesis
- Receptors, Serotonin -- metabolism
- Serotonin Antagonists -- chemical synthesis
- Software
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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