A selective ATP-binding cassette subfamily G member 2 efflux inhibitor revealed via high-throughput flow cytometry. [electronic resource]
Producer: 20130604Description: 26-38 p. digitalISSN:- 1552-454X
- ATP Binding Cassette Transporter, Subfamily B
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- antagonists & inhibitors
- ATP Binding Cassette Transporter, Subfamily G, Member 2
- ATP-Binding Cassette Transporters -- antagonists & inhibitors
- Animals
- Antineoplastic Agents -- pharmacology
- Cell Line
- Drug Resistance, Neoplasm
- Flow Cytometry
- High-Throughput Screening Assays
- Humans
- Inhibitory Concentration 50
- Mice
- Mice, SCID
- Neoplasm Proteins -- antagonists & inhibitors
- Pyrazoles -- pharmacology
- Pyrimidines -- pharmacology
- Small Molecule Libraries
- Structure-Activity Relationship
- Tumor Burden -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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