Long-term smoking mediated down-regulation of Smad3 induces resistance to carboplatin in non-small cell lung cancer. [electronic resource]
Producer: 20130318Description: 644-55 p. digitalISSN:- 1476-5586
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Biphenyl Compounds -- pharmacology
- Carboplatin -- pharmacology
- Carcinoma, Non-Small-Cell Lung -- genetics
- Cell Line, Tumor
- Drug Resistance, Neoplasm -- genetics
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Lung Neoplasms -- genetics
- Nitrophenols -- pharmacology
- Piperazines -- pharmacology
- Proto-Oncogene Proteins c-bcl-2 -- antagonists & inhibitors
- Smad3 Protein -- genetics
- Smoking -- adverse effects
- Sulfonamides -- pharmacology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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