The mTOR inhibitor rapamycin opposes carcinogenic changes to epidermal Akt1/PKBα isoform signaling. [electronic resource]
Producer: 20130906Description: 3254-62 p. digitalISSN:- 1476-5594
- Agammaglobulinaemia Tyrosine Kinase
- Animals
- Blotting, Western
- Cell Line
- Cell Transformation, Neoplastic -- drug effects
- Epidermis -- drug effects
- Humans
- Immunohistochemistry
- Immunoprecipitation
- Immunosuppressive Agents -- pharmacology
- Isoenzymes -- metabolism
- Keratinocytes -- drug effects
- Mice
- Phosphorylation
- Protein-Tyrosine Kinases -- metabolism
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction -- drug effects
- Sirolimus -- pharmacology
- Skin
- TOR Serine-Threonine Kinases -- antagonists & inhibitors
- Ultraviolet Rays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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