Norcantharidin enhances bortezomib-antimyeloma activity in multiple myeloma cells in vitro and in nude mouse xenografts. [electronic resource]
Producer: 20130722Description: 607-18 p. digitalISSN:- 1029-2403
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Blotting, Western
- Boronic Acids -- pharmacology
- Bortezomib
- Bridged Bicyclo Compounds, Heterocyclic -- pharmacology
- Caspases -- metabolism
- Cell Cycle Checkpoints -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Dose-Response Relationship, Drug
- Drug Synergism
- Flow Cytometry
- Humans
- I-kappa B Kinase -- metabolism
- I-kappa B Proteins -- metabolism
- Male
- Mice
- Mice, Nude
- Multiple Myeloma -- drug therapy
- NF-KappaB Inhibitor alpha
- NF-kappa B -- metabolism
- Pyrazines -- pharmacology
- Signal Transduction -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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