Rapamycin ameliorates age-dependent obesity associated with increased mTOR signaling in hypothalamic POMC neurons. [electronic resource]
Producer: 20121018Description: 425-36 p. digitalISSN:- 1097-4199
- Action Potentials -- physiology
- Aging -- physiology
- Animals
- Eating -- physiology
- Hypothalamus -- drug effects
- Immunohistochemistry
- KATP Channels -- metabolism
- Mice
- Mice, Transgenic
- Multiplex Polymerase Chain Reaction
- Neurons -- drug effects
- Neurotransmitter Agents -- pharmacology
- Obesity -- physiopathology
- Organ Culture Techniques
- Patch-Clamp Techniques
- Pro-Opiomelanocortin -- metabolism
- Signal Transduction -- physiology
- Sirolimus -- pharmacology
- TOR Serine-Threonine Kinases -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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